Publications

Sciencedirect

The G-quadruplex ligand CX-5461 inhibits laryngeal cancer via inducing immunogenic cell death and remodeling the tumor immune microenvironment

Aug

19

2026

Nucleic Acids Research

G-quadruplex DNA reprograms the photochemistry of CX-5461 toward radical-driven anticancer activity

Aug

12

2026

CANCER RESEARCH

Photodynamic activation of CX-5461 enhances its anti-tumor efficacy

Apr

03

2026

British Journal of Cancer

Targeting ribosomes reprograms the tumour microenvironment and augments cancer immunotherapy

Jul

11

2025

ASH PUBLICATIONS

Targeting WDR5/ATAD2 signaling by the CK2/IKAROS axis demonstrates therapeutic efficacy in T-ALL

Mar

27

2025

Communications Biology

Fibroblast growth receptor 1 is regulated by G-quadruplex in metastatic breast cancer

Aug

09

2024

Biomedicines

CX-5461 Preferentially Induces Top2α-Dependent DNA Breaks at Ribosomal DNA Loci.

Jul

08

2024

Drugs

Treatment of Ovarian Cancer Beyond PARP Inhibition: Current and Future Options

Sep

22

2023